Cialis is known to contradict with the following medications:

Nitrates – Cialis is not recommended for patients using any form of organic nitrate, either regularly and/or intermittently. In clinical trials, Tadalafil was shown to potentiate the hypotensive effect of nitrates due to the combined effects of nitrates and tadalafil on the nitric oxide/cGMP pathway. This leads the blood pressure to drop to dangerous levels.

Alpha Blockers – Cialis is not recommended for patients taking any alpha-blockers because of the blood-pressure-lowering effect.

Hypersensitivity -Patients with a known hypersensitivity to tadalafil or any component of the tablet should not take it.



Patients with cardiovascular problems should avoid taking Cialis. There is a risk of cardiac arrest in patients for whom sexual activity is inadvisable. Similarly, Cialis is not recommended for patients suffering from cardiovascular diseases like:

  • patients with a myocardial infarction within the last 90 days
  • patients with unstable angina or angina occurring during sexual intercourse
  • patients with greater heart failure in the last 6 months
  • patients with uncontrolled arrhythmias, hypotension (<90/50 mm Hg), or uncontrolled hypertension (>170/100 mm Hg)
  • patients with a stroke within the last 6 months

In addition, patients with known hereditary degenerative retinal disorders, including retinitis pigmentosa.

Cialis Prolonged Erection

Patients who have an erection lasting greater than 4 hours, whether painful or not, should seek emergency medical attention.


Before you buy CIALIS, it is important to identify potential underlying causes, as well as treatment options for Erectile Dysfunction.